CAR T Cell Therapy Step-by-Step
Step 3: Your Treatment
Lymphodepleting Chemotherapy
Depending on your disease and the CAR T therapy you are receiving, you will receive chemotherapy prior to your CAR T infusion. This chemotherapy is commonly known as lymphodepleting chemotherapy and helps prepare your body for the CAR T cells.
Depending on your CAR T treatment center as well as aspects of your specific disease, your doctor will decide whether you will receive your treatment in an inpatient or an outpatient setting.
CAR T Cell Therapy Infusion Process
Your CAR T cell therapy healthcare team will let you know the details about your CAR T treatment such as the date of infusion and when to arrive at the treatment center. CAR T cell infusion typically occurs a few days after lymphodepleting chemotherapy. The steps of the infusion process are outlined below.
Your Team
May consist of:
- Medical Oncologist
- Specialized Nurse(s)
- Caregiver
Estimated Duration
- Lymphodepleting Chemotherapy: 3-4 days
- Infusion: ≥1 hour
- Your CAR T cells will be stored until the start of your infusion. Prior to the infusion, you may receive medications, such as diphenhydramine, to reduce the risk of an allergic reaction.
- Your CAR T cells will be infused via an IV line and they may be in an infusion bag or a syringe, depending on the product.
- The infusion time varies, but can usually be completed over the course of 1 hour.
- The day you receive your CAR T cells, you may remain in the hospital or be discharged, depending on what you and your doctor decide is best.
- You will require frequent monitoring or check-ins immediately after CAR T infusion.
How You Can Prepare
To prepare for the CAR T cell therapy infusion process, consider asking your treatment center or CAR T cell therapy manufacturer about the availability of educational resources and/or support programs that may include financial assistance with lodging, transportation, and meals. Resources and financial support may vary by product manufacturer and eligibility requirements may apply.
Your Resources
The CAR T Cell Therapy Process
Learn More about the CAR T cell therapy treatment process and possible side effects in this step-by-step guide.