CAR T Cell Therapy Step-by-Step

Step 2: Before Your Treatment

Collecting Your T Cells

Your blood will be collected in a procedure known as apheresis, or leukapheresis.

apheresis

During the blood collection procedure, your healthcare team will make you comfortable in a reclining chair or bed. A nurse will collect your blood via an IV line and filter the blood through a machine to collect some of your immune cells, called T cells.

 

apheresis

After the T cells are filtered out, the remaining blood is returned right back to your body. Your T cells will be sent to a lab to become soldiers personalized for your disease.

 

 Your Team

    May consist of:

  • Medical Oncologist
  • Specialized Nurse(s)
  • Caregiver

 Estimated Duration

  • 2-5 hours

What Happens to Your T Cells

apheresis

At the lab, your T cells will be given a specific receptor (or hook) called the chimeric antigen receptor (CAR). Once armed, your CAR T cells will use their new receptors to find and attack target cells in your body while some healthy cells may be affected too.

apheresis

Continue life as usual while you wait for your CAR T cells. In some cases, your doctor may want to give treatment for your disease during this time.  This therapy is frequently called “bridging therapy".

How You Can Prepare

 

Plan to wear loose comfortable clothing and bring some entertainment to pass the time the day of apheresis.

While your cells are at the lab being manufactured, you may also consider planning some activities that you find enjoyable, such as spending time with family and friends, and participating in hobbies like reading or taking a walk outdoors.

Talk to your doctor about what is best for you.

Your Resources

The CAR T Cell Therapy Process

Learn more about the CAR T cell therapy treatment process and possible side effects in this step-by-step guide.

Understanding Apheresis

Get more information about the blood collection (apheresis) process, including what to expect before, during, and after the collection.